Schools Served
Any eligible student enrolled in the 9th, 10th or 11th grade in any Arkansas high school may apply to participate in the Lyon College Upward Bound Math-Science Program, however, special consideration is given to students who attend the following schools:
| Augusta High School | Mtn. View High School |
| Blytheville High School | Nettleton High School |
| Cave City High School | Newport High School |
| Clinton High School | Norfork High School |
| Cross County High School | Palestine-Wheatley High School |
| Cushman High School | Pocahontas High School |
| East Junior High School | Shirley High School |
| East Poinsett County High School | Tuckerman High School |
| Hoxie High School | West Junior High School |
| Hughes High School | West Memphis High School |
| Mammoth Spring High School | Williford High School |
|
Marshall High School |